Congratulation to the Fenteany group! They recently published in Synlett regarding a methodology for the preparation of oxazolidinone and tosyl amines using simple tertiary amines to catalyze the reaction! Check it out:
So those who must not be named are actually cooperating for once. Professor Tilley and I just sent the revisions to our manuscript back to Organic Letters and they were immediately accepted. As for the timetable for publication, next week we will get the proofs back for our manuscript and I will have to literally go word by word and make sure the publishers formatted the document correctly. I can’t believe it’s finally done! I’m very excited to see my name up in the ASAPs and I’ll be sure to post all the information here in the pubs section. I’m also working on some other things with Professor Tilley and a possible collaboration with Professor Leadbeater so stay tuned on new from that lead. So even more good news: my second article, the one that got rejected from Organic and Bimolecular Chemistry has been resubmitted to another journal, Organic Process Research and Development. Hopefully, I will know by the end of the month on the result of that. I’d be pretty happy with two ACS publications in less than a month :P. Now for the kicker. I just finished a project!!! It took roughly about a month of hard work but we will be submitting it to Catalyst Communications either tomorrow or Monday. Again, I’ll be sure to keep you updated on that as well. So now comes the hard part: new projects. I think that’s probably the hardest aspect of any graduate student’s career mostly because of my discussion in an earlier post. Plus you feel a sense of complacence because you are kind of owning science (or at least you think so because you defeated the “evil” reviewers and editors of the journal you have submitted to). But the issue is, you need to be a factory of novel and interesting ideas. Not only that, but you have to step outside your comfort zone and trying experiments whose results are unknown (and most likely filled with failure). But, since you know that the only way to escape the clutches of grad school in a reasonable amount of time is to publish publish publish, you need to constantly be motivated. So, that’s the point I’m at right now. I’m excited to go ahead and pick up a few projects, especially with all the new toys in the lab :P.
However, now that I finally have some (and by that I mean the two to three hours at night before I pass out) time, I’d like to reserve just a little commentary on a discussion I was having with a fellow graduate student tonight. This particular student is a 5th year and, since money is tight with his PI, he is TAing for two organic labs, one of which I am also TAing for. Now I’m not going to rant about my students (I’m sure it’s a pastime ubiquitous throughout the graduate student community.) In fact, so far all the classes I’ve taught ( a grand total of three at uconn and one a semester each year at Stonehill from sophomore year on) are generally really sweet and hard workers. However, they are the exception to the rule in my opinion. The majority of today’s students don’t have a good work ethic….or more accurately, they lack one at all. Maybe it is that I am very much invested in chemistry and science itself, but it seems to me with each passing year students get worse and worse while rules at the high school and even college level get more and more lax to accommodate them. And this grad student and I aren’t the only ones that think so. A story was recently released regarding a teacher, who ironically has a blog, posted about the poor quality of her students. It confirmed many of my observations and I can conclude this is a larger phenomenon than I thought. So I think American students really need to step up their game when it comes to academics. I know our culture today no longer stresses academics and that makes me sad. I feel that, if we are to continue on this path, we will be buried by the advancement of other nations. We need to be the leaders of technology and science and the only way to do that is to have a well-educated, interested student base! Well, that’s enough ranting for one night. I promise the next post will be a review. I’ve seen a couple of articles that really impressed me!…Ckellz…Signing Off…
I can’t say I can think of anything more scary for any food service employee than a pack of graduate students. Like hyenas descending on a limping antelope, grad students appear and within mere minutes all that is left is some bone that has been picked clean, some half-eaten pizza crusts and a tray of Brussel sprouts. You would think that these young adults hadn’t eaten a morsel in their lives (but in reality they ate, on average, a mere hour ago…). Now, I am no exception to this rule, as my peers at both Stonehill and UConn know. I can demolish food with the best of them, though my tastes are slightly different from my comrades in chemistry (mountains of fruit fall to my hunger).
Now I am convinced that if you put the term “free food” in the context of any notification, you are sure to have graduate students appear (even if they aren’t explicitly invited). So long as the event does not prohibit graduate student attendance, they will be there (oddly enough they would show up at almost the exact time the food is served). The allure of food is (almost) enough to get most students to attend all of the guest or faculty seminars (though most times they pull a “pearl harbor”: sneak in, take out half a tray of cookies, stuff some in their pockets, and evacuate back to their lab before anyone knows what happened). You would think by now that at the end of every thesis template they would put…”And if you complete this ahead of schedule, you will be treated to the restaurant of your choice on the university’s tab”. How much more of an incentive would a grad student need?
Now being the scientist that I am, I tried to rationalize why this “free food” phenomena occurs. Is it that graduate students have overactive metabolisms? Is it the fact that the majority of us get paid less than minimum wage? Or is it some synergistic effect of free and food that makes the graduate student such a force to be reckoned with at the dinner table? And what of the “pearl harbor” observation?
Since I currently am snowed in, I really don’t have access to the pool of data that I would want. I merely can tell you based on past experiences and my own thoughts on what the ravenous hunger of the grad student stems from. I tend to believe that the food cravings of the grad student more relate to their income than to actual metabolism. I mean we do work 10 to 12+ hours per day on average and we are likely to be somewhat more hungry than the average joe but not to the point of constant hunger. So to offer them something that saves them money and could even makes them more productive by saving them time preparing a meal or cooking one is greatly appealing (I know that last part may be a stretch but I think you get the point). But why do we eat as if we have been stranded on an island for weeks? Well I can liken it to the insanity that occurs in supermarkets before winter storms. People shop not because they think they will be forever snowed in, but because they don’t know when they will have time again to get out and shop due to the disruption of their regular schedule. Grad students consume like they do because they have such busy schedules that they don’t know they will have time again later. But what about “pearl harboring”. I think the same principle applies. Grad students are so focused on their work they it takes a really strong force to pull them away from it. Food is good enough but at the expense of losing time to a seminar they could care less about, they take the less demanding hit-and-run path (like most chemical reactions :P).
So that’s it for today. Hopefully this snow storm doesn’t seal me in my apartment for the rest of the week (although its not looking too promising right now). I have some interesting news coming shortly and a new review on its way so stay tuned! Ckellz…Signing off…
Principle Investigator. Its science’s fancy name for the guy who funds you to do lab work for him. Basically it translates to “your boss”. Now I mention in an earlier post that one of the perks of being a grad student is you get to choose your boss. And to use another fancy sciencey term, this choice is unprecedented as compared to most other fields. In most corporate structures, you are assigned a supervisor. Whether you like him or not isn’t something that the company considers. And he essentially controls your livelihood and, in part, your life. My dad works for AT&T (via several buy-outs of other companies). But I can tell you, he’s gone through several bosses. You can really tell when he has a shitty one and a good one. Like right now he has one that is really considerate and not overly demanding. Compared to his last one, that’s a god-send. So that choice that us grad students get is quite unique and extremely important. I was very lucky as an undergrad. I got paired up with a man who I can truly call one of my best friends, Dr. Leon Tilley. He introduced me to chemistry at the college level and to research. He is still the person I call when I have a question I just can’t answer or a suggestion for an idea. But I didn’t really chose him as my PI, it just sort of worked out that way. Now when I came to UConn, I needed to make a choice as to who to work for. It was one of the most difficult choices I’ve had to make. Now you may be like im being overly dramatic, but I’d come up with not only a list why this choice is critical but also some qualities to look for in a good PI. Bear in mind that neither of my PIs have all of these qualities, but so long as the ones important to you are met, that person is probably a safe bet:
Why is this choice so important:
• You will be working for this person for the next 4-6 years of your life. You will undoubtedly be spending an ample amount of time with him or her. Do you really want to have to meet with someone you are uncomfortable with for more than half a decade?
• The research that you do as an graduate student is dictated by your PI. This means (most of the time) you become his disciple. The work you will do upon graduation will most likely have something to do (if not be identical) to the work you were doing as a graduate student. So essentially even after you leave you Ph.D. lab, your PI will still be haunting you 😛
• Jobs. The work you do and the reputation of your PI will ultimately determine you likelihood at getting that dream job, be it in pharma or in academia.
• Publications and Timeliness. Your PI also determines how long your indentured servitude lasts and how well known you are in your field based on how often he publishes.
Questions to ask:
• Funding: What are your sources? Are they relible and renewable? How much? How often does this potential PI apply for grants? (If your PI is writing grants too often, you will never see him. However if not often enough, you will be underfunded. I am not of the school of thought that believes you PI’s only job is to get your group money; there needs to be time to talk to your PI. You generally want NIH or NSF funding because its that’s not easy to get, meaning that PI is doing impactful work. and it can be renewed. And as will most things in life, the more money the better.)
• Publications: How often does he published? Is it at least more than once a year? How often has he published in the past three years? How many students have several publications? Where does he publish? Is this the kind of journal you want to be publishing in? (Depending on the types of journals and the number of students a PI has working for him, how often he published is relative. However if you look at the first three questions, you can get a general prediction on how many pubs you can expect to see working in his lab. I would say don’t restrict yourself to a PI that only publishes to ACS journals. They are hard to get into and you may only walk away with one publication. I know the old saying is quality over quantity but I’d take a few OBC papers* over a single JOC paper during my career as a graduate student. Its important to get as many publications as possible so look for repeat names on their papers!)
• Website, Technology and Age: Does the group have a website? Is it well maintained and up-to-date? Does the PI have a grasp on the current tools available to chemists? Is he willing to purchase new tools? How old is the PI and when did that PI get Tenure? (Unlike previous generations, our generation grew up with the internet. So we have a tendency to want to see things as up-to-date as possible. And moreover its not hard to maintain a webpage with all the tools available today like Dreamweaver or its open-source alternative nVu. So look for a well maintained page, it means the PI is up on the times. Technology is also key in the lab. My group is well-known for microwave chemistry and we are slowly acquiring flow reactors to get into that as well. Not only does this give you experience but it would likely lead to publications just simply by using a new instrument. Now for the weird question age and tenure. It’s important to chose a PI who is tenured. I wouldn’t risk your research on the chance that your PI could lose his position at your institution. That being said, I would recommend that you look for someone that just recently has acquired tenure. They are likely to be highly active in their field because they still have the pre-tenure publish-as-much-as-possible mentality. However, they may be not as…harsh…as they were pre-tenure. I also tend too look for younger PIs just because you are more likely to relate to them/they are more likely to be up on the times. That is not a rule but a trend I’ve seen.)
• Communication and Personality: Does he seem like a reliable nice guy? Is he “driven” or demanding? Is he prompt at replying to e-mails? Does he use text messaging? Does he care about his students (I think these are sort of obvious questions except for the text messaging one. I really love the fact that my PI and former PI use text messaging. Its very convenient when you are in a situation where e-mail is just too slow.)
So that’s all I got for today. Just my thoughts on PIs and what you should look for. By no means are these all the criteria you should look for. And these are only my opinions, what you look for will vary from what I do. However, I hope these thoughts give you some guidance if you are reading and you are a pre-grad student or if you are currently looking for a PI! Ckellz…Signing off….
*As a side note, we unfortunately got rejected from Organic and Biomolecular Chemistry because we got one bad reviewer. We are either going to appeal or resubmit elsewhere. It was a disappointment but not the first time I’ve had an article rejected. So just keep your fingers crossed for me and I will update you on the status of that article.
The lab next to mine just got a paper in Organic and Biomolecular Chemistry! Pretty cool stuff check it out:
Iodination of anilines and phenols with 18-crown-6 supported ICl2-
Okay, so many of you may know that the thing that graduate students complain most about is probably a combination of two things: A. I don’t get paid enough for this shit and B. Why am I still here, I’ve been here for over 16 hours! Now as I graduate student, I have my own bias but I will try to put that aside here for one second. Let’s address point A first. I’d like to point out that the job requirements of a TA/RA are daunting. Not only do you have to teach, but you need to keep your PI satisfied by occasionally performing an experiment (and by occasionally I mean every day), take some classes on the side (and pass them), grade lab reports where you spend more time working on the students’ labs then they actually did writing the labs up, and being generally underappreciated. But wait, I said I was gonna leave personal bias behind. Well, the statement was I don’t get paid enough for this shit. In fact that’s flat out wrong. Let’s consider that you are getting not only a salary (and compared to salaries of grad students past, a comfortable salary) but an education. A Ph.D., the most prestigious degree one can have in a scientific field. Sure, it may demean you to teach what you’ve learned a million times over to freshman or sacrifice your Friday nights just to grade. I won’t take that away. But consider that your job is pretty much guaranteed. I mean at least at UConn, it’s pretty hard not to have funding. I’d say that’s true for most reputable graduate programs. Moreover, in how many other professions do you get to CHOOSE your boss. Not many, especially in the corporate environment. So, while you won’t be buying that elusive Camaro any time soon, you are far from impoverish. Now point B. Hours for a graduate student are almost self-made. Notice I said almost. You still need to do the bare minimum and fulfill your TA duties and class work. But let’s say you are a full RA, what about then? Well you may still have class work but really your hours are up to you. The time you spend in lab does not correlate directly to productivity. In fact you can spend 16 hours in lab and accomplish not a damn thing if you aren’t working smart. That’s the key, working with a purpose. And that’s why many Ph.D students end up in graduate school longer than they would want to be. They aren’t playing it smart. So what do I mean? Am I just being a stuck-up know-it-all dick? No, that’s not my way. What I like to do to feel like I’m getting stuff done and leave at a reasonable hour is the following: If I have a reaction going for 1 hour, I try and pick out things you can do while I’m waiting (like the infamous glassware or, worse, hood cleaning. Maybe I’ll set up them in such a way that when the first one is done, I begin working it up. Then when the workup for that is done, my next reaction is just finishing up and I’m ready to start my next workup. I know that may seem stressful but you become an assembly line of productivity (and your PI loves you!). Now my labmate’s (and amazing girlfriend) know I’m obsessed with organic, so I have no problem going in at 8am and leaving at 8pm. But that’s usually because I want to get shit done. I feel the urge to. I WANT to get out in 4 years. And I think that’s what every grad student should think about. How will this help me get out early? /end rant…I promise my next post will be a review, I just need to find that right piece to critique :P…Ckellz….Signing off